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PMID: 4332242 Published · ppublish English Journal Article

The 3'-terminal nucleosides of the high molecular weight RNA of C-type viruses.

Maruyama HB, Hatanaka M, Gilden RV

Abstract

Tumor virus RNAs from several mammalian and one reptilian species were purified; their 3'-terminal nucleoside was identified by separation of the trialcohols produced by periodate oxidation followed by reduction and tritiation with NaB(3)H(4). Each virus contained uridine as the predominant terminal nucleoside. Molecular weight estimations based on the tritiation reactions were consistent with a structure consisting of four subunits.

MeSH Terms
Adenosine/analysis Animals Autoradiography Cats Chromatography, Thin Layer Cricetinae Cytidine/analysis Escherichia coli Guanosine/analysis Hydrolysis Leukemia Virus, Murine/analysis Mice Molecular Weight Nucleosides/analysis Oncogenic Viruses/analysis RNA Viruses/analysis RNA, Bacterial/analysis RNA, Transfer/analysis RNA, Viral/analysis Snakes Tritium Uridine/analysis
Chemicals
Nucleosides RNA, Bacterial RNA, Viral Tritium Guanosine Cytidine RNA, Transfer Adenosine Uridine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Maruyama H B
Hatanaka M
Gilden R V
References (12)
12 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
Published
1971-09-00
Pages
1999-2001
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC389334
Subset
IM
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