Inhibition of cyclic-3',5'-nucleotide-phosphodiesterase as a possible mode of action of papaverine and similarly acting drugs.

Naunyn-Schmiedebergs Archiv fur Pharmakologie ·Vol. 267 ·No. 2 ·1970-00-00 ·Pages 189-94

Kukovetz WR, Pöch G

Abstract

暂无摘要

MeSH Terms

Adenine Nucleotides/metabolism Animals Cattle Coronary Vessels/enzymology Cyclic AMP/metabolism Depression, Chemical Dipyridamole/pharmacology Isoquinolines/pharmacology Muscle, Smooth/drug effects Myocardium/enzymology Papaverine/administration & dosage,pharmacology Phosphoric Monoester Hydrolases/antagonists & inhibitors Prenylamine/pharmacology Theophylline/pharmacology Vasodilator Agents/pharmacology

Chemicals

Adenine Nucleotides Isoquinolines Vasodilator Agents Dipyridamole Theophylline Papaverine Cyclic AMP Phosphoric Monoester Hydrolases Prenylamine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Kukovetz W R

Pöch G

References (9)

9 references, click to expand

[Influence of cardio- and vasoactive substances on phosphodiesterase activity].
Naunyn Schmiedebergs Arch Pharmakol. 1969;264(3):293-4 PMID: 4310614
Cardiostimulatory effects of cyclic 3',5'-adenosine monophosphate and its acylated derivatives.
Naunyn Schmiedebergs Arch Pharmakol. 1970;266(3):236-54 PMID: 4316610
Effect of epinephrine on cyclic adenosine 3',5'-phosphate and hexose phosphates in intestinal smooth muscle.
Biochim Biophys Acta. 1966 Jan 25;115(1):173-8 PMID: 5936233
Properties of cyclic 3',5'-nucleotide phosphodiesterase from rat brain.
Biochemistry. 1967 Apr;6(4):1079-87 PMID: 4291761
Electrochemical aspects of physiological and pharmacological action in excitable cells. II. The action potential and excitation.
Pharmacol Rev. 1958 Jun;10(2):165-273 PMID: 13566965
Electrochemical aspects of physiological and pharmacological action in excitable cells. I. The resting cell and its alteration by extrinsic factors.
Pharmacol Rev. 1958 Mar;10(1):59-164 PMID: 13542169
Relaxation of the guinea-pig tracheal chain preparation by N6,2'-O-dibutyryl 3',5'-cyclic adenosine monophosphate.
J Pharm Pharmacol. 1968 May;20(5):368-72 PMID: 4385440
The determination of enzyme inhibitor constants.
Biochem J. 1953 Aug;55(1):170-1 PMID: 13093635
[Mechanism of action of papaverine on isolated coronary vessels].
Naunyn Schmiedebergs Arch Pharmakol. 1969;264(3):262-3 PMID: 4310612

Article Info

Journal

Naunyn-Schmiedebergs Archiv fur Pharmakologie

Abbr.

Naunyn Schmiedebergs Arch Pharmakol

DOI

10.1007/BF00999402

Published

1970-00-00

Pages

189-94

Language

English

Region

Germany

NLM ID

0326263

Subset

External Links

PubMed source DOI: 10.1007/BF00999402

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Inhibition of cyclic-3',5'-nucleotide-phosphodiesterase as a possible mode of action of papaverine and similarly acting drugs.

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