Serological studies with human papova (wart) virus.

The Journal of hygiene ·Vol. 68 ·No. 3 ·1970-09-00 ·Pages 479-90

Ogilvie MM

Abstract

Methods for demonstrating antibody to wart virus by complement fixation and passive haemagglutination tests are described and compared with the precipitin test of Almeida & Goffe (1965). The results reveal the much greater sensitivity of the passive haemagglutination method, particularly in the detection of the immunoglobulin M class of antibody. Both complement-fixing and precipitating antibody were detected in sera from patients whose warts had undergone a spontaneous resolution.The presence of antibody to wart virus was demonstrated in sera from persons who had had warts up to 10 years previously, and in a few cases from those who thought they had never had warts.The antigenic identity of virus from hand warts and plantar warts of the simple and mosaic types was revealed, and some evidence was obtained for similar identity of the virus from genital warts.

MeSH Terms

Adolescent Adult Animals Antibodies/analysis Complement Fixation Tests Female Foot Diseases/immunology Genitalia Hand Hemagglutination Tests Humans Immunoglobulin M Microscopy, Electron Papillomaviridae/immunology Precipitin Tests Rabbits Sheep Warts/immunology

Chemicals

Antibodies Immunoglobulin M

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Ogilvie M M

References (21)

21 references, click to expand

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Article Info

Journal

The Journal of hygiene

Abbr.

J Hyg (Lond)

ISSN

0022-1724

DOI

10.1017/s0022172400042388

Published

1970-09-00

Pages

479-90

Language

English

Region

England

NLM ID

0375374

PMCID

PMC2130829

Subset

External Links

PubMed source DOI: 10.1017/s0022172400042388 PMC Full Text View journal details

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