Localization of kininogenase in the rat kidney.
1. The rat kidney kininogenase (KGA) activity was located mainly in the kidney cortex.2. Differential centrifugation of kidney cortex homogenate revealed that the microsomal fraction contained more KGA activity per unit of protein than the other subcellular fractions.3. Subfractionation of the microsomal fraction showed that the KGA activity was recovered in a subfraction also containing high specific activity of both alkaline phosphate and glucose-6-phosphatase. It is suggested that the KGA activity is localized in the plasma membrane and/or endoplasmic reticulum membranes of kidney cortical cells.4. Hydrolysis of N-alpha-benzoyl-L-arginine ethyl ester at pH 8.5 paralleled the KGA activity.
21 references, click to expand
-
[On the release of a kallikrein-like substance by extracts of various organs].Arch Int Pharmacodyn Ther. 1961 May 1;131:257-61 PMID: 13784435
-
[On behavior of the kininogen level following renal and adrenal extirpation in rats].Hoppe Seylers Z Physiol Chem. 1968 Jan;349(1):107-8 PMID: 4174406
-
Tissue fractionation studies. VII. Release of bound hydrolases by means of triton X-100.Biochem J. 1956 Aug;63(4):606-8 PMID: 13355857
-
Histochemical staining reactions of the normally functioning and abnormal kidney.J Histochem Cytochem. 1955 Jul;3(4):246-70 PMID: 13242782
-
Tissue fractionation studies. 12. Intracellular distribution of some dehydrogenases, alkaline deoxyribonuclease and iron in rat-liver tissue.Biochem J. 1959 Dec;73:623-8 PMID: 13797961
-
Enzymology of kidney tissue.Curr Probl Clin Biochem. 1968;2:119-45 PMID: 4359230
-
Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue.Biochem J. 1955 Aug;60(4):604-17 PMID: 13249955
-
The determination of nucleic acids in biological materials. A review.Analyst. 1961 Dec;86:768-813 PMID: 14450260
-
Principles of tissue fractionation.J Theor Biol. 1964 Jan;6(1):33-59 PMID: 5875177
-
Quantitative histochemistry of the nephron. II. Alkaline phosphatase activity in man and other species.J Clin Invest. 1960 Sep;39:1372-80 PMID: 13802623
-
Subfractionation and composition of microsomal membranes: a review.J Histochem Cytochem. 1968 Oct;16(10):611-32 PMID: 4880002
-
[The hexose-phosphatase system. III. Intracellular localization of enzymes by fractional centrifugation].Bull Soc Chim Biol (Paris). 1951;33(1-2):21-41 PMID: 14935564
-
[On the excretion of kallikrein in urine after experimental kidney injury].Arch Int Pharmacodyn Ther. 1960 Jun 1;126:171-86 PMID: 13844022
-
THE LOCALIZATION OF PHOSPHATASE ACTIVITIES AT THE LEVEL OF ULTRASTRUCTURE.J Histochem Cytochem. 1964 Feb;12:72-95 PMID: 14187314
-
Renal acid phosphatase: a biochemical study.Lab Invest. 1966 Dec;15(12):1848-55 PMID: 5960460
-
Tissue fractionation studies. 17. Intracellular distribution of monoamine oxidase, aspartate aminotransferase, alanine aminotransferase, D-amino acid oxidase and catalase in rat-liver tissue.Biochem J. 1964 Jul;92(1):179-84 PMID: 4378796
-
Protein measurement with the Folin phenol reagent.J Biol Chem. 1951 Nov;193(1):265-75 PMID: 14907713
-
Kinin-forming enzyme (kininogenin) in homogenates of rat kidney.Biochim Biophys Acta. 1966 Oct 17;128(1):136-48 PMID: 5972354
-
Lysosomes in rat-kidney tissue.Biochim Biophys Acta. 1965 Sep 20;105(3):446-59 PMID: 4285898
-
The relationship between kidney and urinary kininogenase.Br J Pharmacol. 1970 May;39(1):73-86 PMID: 5420147
-
Urinary excretion of kinin in man with special reference to its origin.Tohoku J Exp Med. 1965 Nov 25;87(2):175-84 PMID: 5864169
Contact
No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong
Qilu Normal University · Genelibs Bioinformatics Lab
750 Shunhua Rd, Jinan
2F, Bldg F, University Science Park
Tel: 0531-88819269
WeChat Official Account
Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.
Business Email
E-mail: product@genelibs.com
Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2
