Myxovirus antibody increases in human connective tissue disease.

Science (New York, N.Y.) ·Vol. 168 ·No. 3934 ·1970-05-22 ·Pages 982-4

Phillips PE, Christian CL

Abstract

Antibodies to measles and parainfluenza type 1 viruses were significantly increased in systemic lupus erythematosus and Reiter's syndrome. Of the individuals with highest titers of measles antibody, 75 percent had neurologic illness. Persistent virus infection may be a factor in the pathogenesis of these diseases.

MeSH Terms

Antibodies/analysis Arthritis, Juvenile/immunology Arthritis, Reactive/immunology Arthritis, Rheumatoid/immunology Complement Fixation Tests Diffuse Cerebral Sclerosis of Schilder/immunology Hemagglutination Inhibition Tests Humans Lupus Erythematosus, Systemic/immunology Measles/immunology Measles virus/immunology Paramyxoviridae Infections/immunology Respirovirus/immunology

Chemicals

Antibodies

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Phillips P E

Christian C L

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.168.3934.982

Published

1970-05-22

Pages

982-4

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.168.3934.982 View journal details

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Myxovirus antibody increases in human connective tissue disease.

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