Familial systemic paramyloidosis with lattice dystrophy of the cornea, progressive cranial neuropathy, skin changes and various internal symptoms. A previously unrecognized heritable syndrome.

Adult Age Factors Amyloidosis/genetics Blood Protein Electrophoresis Brain Diseases Corneal Dystrophies, Hereditary/genetics Female Finland Humans Male Middle Aged Pedigree Peripheral Nervous System Diseases/genetics Skin Diseases/genetics