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PMID: 4313302 Published · ppublish English Journal Article

Intestinal enzymes: indicators of proliferation and differentiation in the jejunum.

Science (New York, N.Y.) ·Vol. 167 ·No. 3925 ·1970-03-20 ·Pages 1627-8

Fortin-Magana R, Hurwitz R, Herbst JJ, Kretchmer N

Abstract

Some intestinal enZymes were assayed which were related to: (i) Cellular proliferation, for example, aspartate carbamoyltransferase, thymidine kinase, uridine kinase, and dihydroorotase; (ii) cellular differentiation, for example, lactase, invertase, maltase, alkaline phosphatase, and dipeptidase; and (iii) lysosomes, for example, beta-glucuronidase, acid beta-galactosidase, and acid phosphatase. These enzymatic determinations can be used to distinguish the crypt from the villus during healthy or diseased states.

MeSH Terms
Animals Cell Differentiation Cell Division Galactosidases/analysis Glucuronidase/analysis Glycoside Hydrolases/analysis Histocytochemistry Intestinal Mucosa/enzymology Jejunum/enzymology Lysosomes/enzymology Phosphoric Monoester Hydrolases/analysis Phosphotransferases/analysis Rats Thymidine Kinase/analysis Transferases/analysis
Chemicals
Transferases Phosphotransferases Thymidine Kinase Phosphoric Monoester Hydrolases Galactosidases Glycoside Hydrolases Glucuronidase
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Fortin-Magana R
Hurwitz R
Herbst J J
Kretchmer N
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1970-03-20
Pages
1627-8
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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