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PMID: 4309882 Published · ppublish English Journal Article

Replication of canine herpesvirus. II. Virus development and release in infected dog kidney cells.

Journal of virology ·Vol. 4 ·No. 4 ·1969-10-00 ·Pages 480-9

Strandberg JD, Aurelian L

Abstract

The studies reported in this paper demonstrate that, although canine herpesvirus differs from other herpesviruses in that it is characterized by a restricted host range, the pattern of virus development in the permissive host closely resembles that previously described for herpes simplex virus. These experiments also reveal the formation in the infected dog kidney cells of a system of tubules and channels in which virions accumulate. It is suggested that these membrane-bound structures serve to protect enveloped virus from being uncoated in the cytoplasm and function in virus release from the infected cells.

MeSH Terms
Animals Cytopathogenic Effect, Viral Dogs Herpesviridae/growth & development Herpesviridae Infections/microbiology,pathology In Vitro Techniques Inclusion Bodies, Viral Kidney Microscopy, Electron Virus Replication
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Strandberg J D
Aurelian L
References (22)
22 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
Published
1969-10-00
Pages
480-9
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC375897
Subset
IM
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