Immunochemical characterization of plaque mutants of simian virus 40.

Journal of virology ·Vol. 3 ·No. 1 ·1969-01-00 ·Pages 17-24

Ozer HL, Takemoto KK, Kirschstein RL, Axelrod D

Abstract

Analysis of large and small plaque mutants of simian virus 40 using antisera prepared against each has revealed quantitative and possibly qualitative antigenic differences for each plaque type. A sensitive micro radioisotope precipitation test permitted evaluation of immunochemical similarities and differences of capsid antigens by inhibition of precipitation.

MeSH Terms

Amino Acids/metabolism Animals Antigens/analysis Carbon Isotopes Complement Fixation Tests Cricetinae Haplorhini Immune Sera Immunochemistry Methods Mice Mutation Phosphorus Isotopes Precipitin Tests Rabbits Simian virus 40/metabolism Viral Proteins/analysis

Chemicals

Amino Acids Antigens Carbon Isotopes Immune Sera Phosphorus Isotopes Viral Proteins

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Ozer H L

Takemoto K K

Kirschstein R L

Axelrod D

References (12)

12 references, click to expand

Hamster ascitic fluids containing complement-fixing antibody against virus-induced tumor antigens.
Proc Soc Exp Biol Med. 1965 Oct;120(1):124-7 PMID: 4285232
Antigenic variation among polyoma viruses from different sources demonstrated by plaque neutralization.
Virology. 1966 Sep;30(1):62-73 PMID: 4287877
Mutants of simian virus 40 differing in plaque size, oncogenicity, and heat sensitivity.
J Bacteriol. 1966 Oct;92(4):990-4 PMID: 4288804
Electron microscopic observations on multiple polyoma virus-related particles.
Virology. 1967 Jul;32(3):378-92 PMID: 4291303
Structure of simian virus 40. I. Purification and physical characterization of the virus particle.
Virology. 1967 Jul;32(3):503-10 PMID: 4291307
Recovery of SV40 virus with genetic markers of original inducing virus from SV40-transformed mouse cells.
Virology. 1968 May;35(1):1-8 PMID: 4297401
Immunochemical studies on the tobacco mosaic virus protein. VI. Characterization of antibody populations following immunization with tobacco mosaic virus protein.
Biochemistry. 1968 Apr;7(4):1253-60 PMID: 5663398
Application of a microtechnique to viral serological investigations.
J Immunol. 1962 Mar;88:320-9 PMID: 13910995
Precipitation of radiolabeled poliovirus with specific antibody and antiglobulin.
J Immunol. 1962 Oct;89:559-70 PMID: 13960496
Purification of polyoma virus.
Virology. 1963 Feb;19:158-68 PMID: 14001211
IMMUNOGLOBULIN ISOANTIGENS (ALLOTYPES) IN THE MOUSE. I. GENETICS AND CROSS-REACTIONS OF THE 7S GAMMA-2A-ISOANTIGENS CONTROLLED BY ALLELES AT THE IG-1 LOCUS.
J Exp Med. 1965 Mar 1;121:415-38 PMID: 14270242
INFLUENCE OF THE STATE OF SUBUNIT AGGREGATION ON THE ANTIGENIC SPECIFICITY OF TMV AND TYMV.
Virology. 1965 Feb;25:325-8 PMID: 14297220

Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.3.1.17-24.1969

Published

1969-01-00

Pages

17-24

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC375724

Subset

External Links

PubMed source DOI: 10.1128/JVI.3.1.17-24.1969 PMC Full Text View journal details

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Immunochemical characterization of plaque mutants of simian virus 40.

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