Regulation of protein synthesis by hemin. Evidence that the hemin-controlled translational repressor inhibits the rate of formation of 40S.Met-tRNAf complexes directly.

Animals Heme/analogs & derivatives Hemin/pharmacology Kinetics Methionine Molecular Weight Peptide Chain Initiation, Translational/drug effects Protein Biosynthesis/drug effects RNA, Transfer/metabolism Rabbits Repressor Proteins/metabolism Reticulocytes/metabolism Ribosomes/metabolism Transcription Factors/metabolism

Repressor Proteins Transcription Factors Heme Hemin RNA, Transfer Methionine