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PMID: 4290531 Published · ppublish English Journal Article

The polyphosphoinositides and other lipids of peripheral nerves.

The Biochemical journal ·Vol. 100 ·No. 1 ·1966-07-00 ·Pages 12-8

Sheltawy A, Dawson RM

Abstract

1. A detailed lipid analysis of the peripheral nerves of the crab (claw, leg), lobster (claw, leg), cow (splenic), hen, rabbit, sheep and monkey (sciatic) is presented. 2. The so-called ;myelinic lipids', cholesterol, sphingomyelin, ethanolamine plasmalogen and phosphatidylserine, occurred in the highest proportion in the lipids of vertebrate myelinated nerves, whereas the percentage of lecithin was greatest in the lipids of non-myelinated nerve fibres of both vertebrates and invertebrates. 3. Triphosphoinositide was found in all nerves examined and its concentration in the extracted lipids supports the concept that it is predominantly localized in the myelin sheath. 4. In crustacean nerve 12-14% of the phospholipids was in the form of alkyl ether phospholipids, which in the lobster were approximately half choline-containing and half ethanolamine-containing.

MeSH Terms
Animals Cattle Cholesterol/analysis Crustacea Glycolipids/analysis Haplorhini Hydrogen-Ion Concentration Lipids/analysis Myelin Sheath/analysis Neurofibrils/analysis Peripheral Nerves/analysis Phosphatidylinositols/analysis Phospholipids/analysis Poultry Rabbits Sheep
Chemicals
Glycolipids Lipids Phosphatidylinositols Phospholipids Cholesterol
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Sheltawy A
Dawson R M
References (37)
37 references, click to expand
  1. Lipids of normal brain.
    Biochem J. 1948;43(4):573-7 PMID: 16748453
  2. Chemistry of myelin development.
    Prog Neurobiol. 1959;4:122-37 PMID: 13823690
  3. The relation of proteolipids and phosphatidopeptides to tissue elements in the bovine nervous system.
    J Neurochem. 1962 Sep-Oct;9:509-18 PMID: 14012446
  4. CHEMICAL AND METABOLIC STUDIES OF RAT MYELIN OF THE CENTRAL NERVOUS SYSTEM.
    Ann N Y Acad Sci. 1965 Mar 31;122:86-94 PMID: 14313517
  5. PHYSICAL STRUCTURE AND BEHAVIOR OF LIPIDS AND LIPID ENZYMES.
    Adv Lipid Res. 1963;1:65-104 PMID: 14248958
  6. Improvements in the method of determining individual phospholipids in a complex mixture by successive chemical hydrolyses.
    Biochem J. 1962 Sep;84:497-501 PMID: 13884048
  7. Polyphosphoinositides in myelin.
    Biochem J. 1965 Sep;96(3):644-50 PMID: 4285893
  8. The ultrastructure of cell membranes and their derivatives.
    Biochem Soc Symp. 1959;16:3-43 PMID: 13651159
  9. A new method for the direct determination of serum cholesterol.
    J Lab Clin Med. 1953 Mar;41(3):486-92 PMID: 13035283
  10. IDENTIFICATION OF ALPHA-GLYCERYL ETHER PHOSPHOLIPIDS AS MAJOR LIPID CONSTITUENTS IN TWO SPECIES OF TERRESTRIAL SLUG.
    J Biol Chem. 1963 Aug;238:2628-31 PMID: 14063283
  11. Phosphorus assay in column chromatography.
    J Biol Chem. 1959 Mar;234(3):466-8 PMID: 13641241
  12. Diphosphoinositide and triphosphoinositide in animal tissues. Extraction, estimation and changes post mortem.
    Biochem J. 1965 Sep;96(3):634-43 PMID: 4285892
  13. LIPID CLASS AND FATTY ACID COMPOSITION OF INTACT PERIPHERAL NERVE AND DURING WALLERIAN DEGENERATION.
    J Am Oil Chem Soc. 1965 Jun;42:492-500 PMID: 14300205
  14. [Paper chromatographic separation of phosphatides. I].
    Biochem Z. 1959;331(3):155-61 PMID: 13651168
  15. STUDIES ON BRAIN GANGLIOSIDES. 3. EVIDENCE FOR THE LOCATION OF GANGLIOSIDES SPECIFICALLY IN NEURONES.
    Can J Biochem. 1964 Nov;42:1587-94 PMID: 14245253
  16. PROTEOLIPIDS. II. ISOLATION OF A PHOSPHATIDYLETHANOLAMINE REQUIRED FOR LIPID-CYTOCHROME C FORMATION.
    Biochim Biophys Acta. 1964 Oct 2;84:618-20 PMID: 14250502
  17. The phospholipids of the erythrocyte 'ghosts' of various species.
    Biochem J. 1960 Nov;77:226-30 PMID: 13720329
  18. STUDIES ON PHOSPHOLIPIDS. 9. THE COMPOSITION OF RAT-LIVER LECITHINS.
    Biochem J. 1963 Aug;88:319-24 PMID: 14063870
  19. THE STRUCTURE OF THE SCHWANN CELL AND ITS RELATION TO THE AXON IN CERTAIN INVERTEBRATE NERVE FIBERS.
    Proc Natl Acad Sci U S A. 1954 Sep;40(9):863-70 PMID: 16589576
  20. Lipids of peripheral nerve.
    Biochem J. 1948;43(4):578-80 PMID: 16748454
  21. The lipid composition of myelin from brain and peripheral nerve.
    J Neurochem. 1965 Aug;12(8):729-34 PMID: 4284742
  22. Chromatographic separation of brain lipids: cerebroside and sulphatide.
    Biochem J. 1961 Jan;78(1):179-85 PMID: 16748866
  23. Distribution of lipids in subcellular particles of guinea-pig brain.
    Biochem J. 1964 Jul;92(1):91-100 PMID: 5840391
  24. Isolation of "kepalin B" from cerebral lipids.
    Biochim Biophys Acta. 1960 Jul 1;41:371-2 PMID: 13835930
  25. 'Phosphatido-peptide'-like complexes formed by the interaction of calcium triphosphoinositide with protein.
    Biochem J. 1965 Oct;97(1):134-8 PMID: 16749093
  26. THE CHEMICAL COMPOSITION OF BOVINE CNS MYELIN.
    Ann N Y Acad Sci. 1965 Mar 31;122:77-85 PMID: 14313516
  27. Concentration of lipids in the brain of infants and adults.
    Biochem J. 1949;44(4):494-8 PMID: 16748551
  28. The occurence of a long-chain ether analogue of phosphatidylethanolamine in brain tissue.
    Biochem J. 1963 Jul;88:56-64 PMID: 14013279
  29. BREAKDOWN OF PHOSPHOLIPIDS IN MILD ALKALINE HYDROLYSIS.
    J Lipid Res. 1963 Jan;4:96-9 PMID: 14167673
  30. A simple method for the isolation and purification of total lipides from animal tissues.
    J Biol Chem. 1957 May;226(1):497-509 PMID: 13428781
  31. The effects of anaesthetics and of convulsants on the lactic acid content of the brain.
    Biochem J. 1938 Nov;32(11):1908-18 PMID: 16746826
  32. The anaerobic metabolism of citrate in rat liver.
    Biochem J. 1959 Jan;71(1):26-32 PMID: 13628527
  33. BINDING OF METAL IONS TO MONOLAYERS OF LECITHINS, PLASMALOGEN, CARDIOLIPIN, AND DICETYL PHOSPHATE.
    J Lipid Res. 1965 Jul;6:341-9 PMID: 14336204
  34. Some lipid characteristics of red cell membranes of various animal species.
    Biochim Biophys Acta. 1961 May 13;49:286-96 PMID: 13705162
  35. THE AMOUNTS AND DISTRIBUTION OF FREE INOSITOL AND FREE AND PROTEIN-BOUND PHOSPHOINOSITIDES IN BRAIN TISSUES.
    J Neurochem. 1963 Oct;10:677-83 PMID: 14087682
  36. A COMPARISON OF THE POLYPHOSPHOINOSITIDE IN HUMAN AND OX BRAIN.
    Biochim Biophys Acta. 1964 Aug 5;84:461-3 PMID: 14230821
  37. Analysis of lipids by spot tests on filter-paper disk chromatograms.
    Biochem J. 1953 Jul;54(4):602-5 PMID: 13058958
Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
DOI
10.1042/bj1000012
Published
1966-07-00
Pages
12-8
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1265086
Subset
IM
External Links
PubMed source DOI: 10.1042/bj1000012 PMC Full Text View journal details
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