Inhibition of receptor-mediated uptake of a lysosomal enzyme into fibroblasts by chloroquine, procaine and ammonia.

Ammonium Chloride/pharmacology Biological Transport/drug effects Cells, Cultured Chloroquine/pharmacology Dextrans/metabolism Dose-Response Relationship, Drug Glycoside Hydrolases/metabolism Iduronidase/metabolism Kinetics Mannosephosphates/pharmacology Procaine/pharmacology Receptors, Drug/metabolism

Dextrans Mannosephosphates Receptors, Drug Ammonium Chloride Procaine Chloroquine Glycoside Hydrolases Iduronidase