A survey of the embryotoxic effects of TCDD in mammalian species.

Environmental health perspectives ·Vol. 5 ·1973-09-00 ·Pages 67-79

Neubert D, Zens P, Rothenwallner A, Merker HJ

Abstract

暂无摘要

MeSH Terms

2,4,5-Trichlorophenoxyacetic Acid/toxicity Abnormalities, Drug-Induced/etiology Amines/toxicity Animals Cleft Palate/chemically induced Cyclophosphamide/toxicity Dexamethasone/toxicity Dioxins/administration & dosage,toxicity Dose-Response Relationship, Drug Drug Synergism Embryo, Mammalian/drug effects Female Fetal Death/chemically induced Fetal Diseases/chemically induced Fetus/drug effects Gastrointestinal Hemorrhage/chemically induced Kidney/abnormalities Mice Mice, Inbred Strains Niacinamide/toxicity Pregnancy Rats Species Specificity

Chemicals

Amines Dioxins Niacinamide Dexamethasone Cyclophosphamide 2,4,5-Trichlorophenoxyacetic Acid

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Neubert D

Zens P

Rothenwallner A

Merker H J

References (9)

9 references, click to expand

Study of the teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat.
Food Cosmet Toxicol. 1971 Jun;9(3):405-12 PMID: 5314812
Toxicology of chlorinated dibenzo-p-dioxins.
Environ Health Perspect. 1973 Sep;5:87-99 PMID: 4270944
Embryotoxic effects in mice treated wtih 2,4,5-trichlorophenoxyacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Naunyn Schmiedebergs Arch Pharmacol. 1972;272(3):243-64 PMID: 4258611
Inhibition of NADP dependent oxidoreductases by the 6-aminonicotinamide analogue of NADP.
FEBS Lett. 1970 Feb 16;6(3):225-228 PMID: 11947380
[New experience with highly toxic chlorinated hydrocarbons].
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1957;232(1):228-30 PMID: 13526831
Teratology studies with 2,4,5-trichlorophenoxyacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Toxicol Appl Pharmacol. 1971 Nov;20(3):396-403 PMID: 5132781
Teratogenic evaluation of 2,4,5-T.
Science. 1970 May 15;168(3933):864-6 PMID: 5309824
Organs as targets of "dioxin" (2,3,7,8-tetrachlorodibenzo-p-dioxin) intoxication.
Naturwissenschaften. 1972 Apr;59(4):174-5 PMID: 5057571
Chemical and toxicological evaluations of isolated and synthetic chloro derivatives of dibenzo-p-dioxin.
Nature. 1968 Nov 16;220(5168):702-3 PMID: 5693929

Article Info

Journal

Environmental health perspectives

Abbr.

Environ Health Perspect

ISSN

0091-6765

DOI

10.1289/ehp.730567

Published

1973-09-00

Pages

67-79

Language

English

Region

United States

NLM ID

0330411

PMCID

PMC1474968

Subset

External Links

PubMed source DOI: 10.1289/ehp.730567 PMC Full Text View journal details

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A survey of the embryotoxic effects of TCDD in mammalian species.

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