Do peripheral nerves contain a factor inducing acetylcholine sensitivity in skeletal muscle?

Experientia ·Vol. 35 ·No. 2 ·1979-02-15 ·Pages 218-9

Vyskocil F, Syrový I

Abstract

A crude extract of the sciatic nerve, eluate of dialyzed nerve extract or 2 folin-positive sephadex fractions induced acetylcholine sensitivity of extrajunctional regions in extensor digitorum longus muscle fibres of the rat, when released from silastic plates implanted for 3--4 days onto the muscle surface.

MeSH Terms

Acetylcholine/pharmacology Animals Cell Differentiation Dose-Response Relationship, Drug Female Membrane Potentials/drug effects Motor Endplate/physiology Neuromuscular Junction/physiology,ultrastructure Peripheral Nerves/physiology Rats Receptors, Cholinergic/drug effects Sciatic Nerve/physiology

Chemicals

Receptors, Cholinergic Acetylcholine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Vyskocil F

Syrový I

References (9)

9 references, click to expand

A protein fraction from peripheral nerve having neurotrophic effects on skeletal muscle cells in culture.
Exp Neurol. 1978 Jan 15;58(2):285-95 PMID: 22454
An investigation of spontaneous activity at the neuromuscular junction of the rat.
J Physiol. 1956 Jun 28;132(3):650-66 PMID: 13332600
Changes in chemosensitivity of skeletal muscles as related to endplate formation.
Prog Neurobiol. 1976;3(2):103-36 PMID: 778916
The acetylcholine sensitivity of frog muscle fibres after complete or partial devervation.
J Physiol. 1960 Apr;151:1-23 PMID: 14422356
An electrophysiological examination of the changes in skeletal muscle fibres in response to degenerating nerve tissue.
Brain Res. 1975 May 2;88(2):309-17 PMID: 1148828
Induction of an extrajunctional chemosensitive area in intact innervated muscle fibres.
J Physiol. 1967 Jul;191(1):20P-21P PMID: 6050619
Protein measurement with the Folin phenol reagent.
J Biol Chem. 1951 Nov;193(1):265-75 PMID: 14907713
Two factors responsible for the development of denervation hypersensitivity.
J Physiol. 1974 Feb;236(3):517-38 PMID: 4822574
Inhibition of cell division and the development of denervation hypersensitivity in skeletal muscle.
Pflugers Arch. 1975 Mar 26;355(3):189-204 PMID: 1170546

Article Info

Journal

Experientia

Abbr.

Experientia

ISSN

0014-4754

DOI

10.1007/BF01920626

Published

1979-02-15

Pages

218-9

Language

English

Region

Switzerland

NLM ID

0376547

Subset

External Links

PubMed source DOI: 10.1007/BF01920626

Analysis Services

Do peripheral nerves contain a factor inducing acetylcholine sensitivity in skeletal muscle?

Contact

WeChat Official Account