Directed mutation in Streptomyces lipmanii.

Bacillus subtilis/drug effects Biological Assay Carbon Radioisotopes Cephalosporins/biosynthesis Cycloserine/pharmacology DNA Replication DNA, Bacterial/biosynthesis Fluorine Genes Hydrogen-Ion Concentration Leucine/metabolism Mutagens Mutation Nitrosoguanidines Penicillin Resistance Penicillins/biosynthesis Pseudomonas/drug effects Salmonella/drug effects Streptomyces/drug effects,metabolism Thymidine/metabolism Tritium Tryptophan/analogs & derivatives,pharmacology

Carbon Radioisotopes Cephalosporins DNA, Bacterial Mutagens Nitrosoguanidines Penicillins Tritium Fluorine Tryptophan Cycloserine Leucine Thymidine