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PMID: 4208292 Published · ppublish English Comparative Study Journal Article

Penicillin-tobramycin synergism against enterococci: a comparison with penicillin and gentamicin.

Antimicrobial agents and chemotherapy ·Vol. 3 ·No. 4 ·1973-04-00 ·Pages 526-9

Moellering RC, Wennersten C, Weinstein AJ

Abstract

Combinations of penicillin plus tobramycin have been compared with penicillin plus gentamicin against 27 strains of enterococci isolated from blood cultures. Penicillin plus gentamicin was synergistic against all strains. The combination of penicillin plus tobramycin was equally effective against strains of Streptococcus facalis, but was ineffective against all four strains of S. faecium tested.

MeSH Terms
Aminoglycosides/pharmacology Anti-Bacterial Agents/pharmacology Drug Synergism Enterococcus faecalis/drug effects Gentamicins/pharmacology Microbial Sensitivity Tests Penicillins/pharmacology Streptococcus/drug effects
Chemicals
Aminoglycosides Anti-Bacterial Agents Gentamicins Penicillins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Moellering R C
Wennersten C
Weinstein A J
References (13)
13 references, click to expand
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    J Infect Dis. 1971 Dec;124 Suppl:S207-9 PMID: 5209574
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    J Infect Dis. 1971 Dec;124(6):581-6 PMID: 5209849
  10. Recognition of group D streptococcal species of human origin by biochemical and physiological tests.
    Appl Microbiol. 1972 Jun;23(6):1131-9 PMID: 4557563
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.3.4.526
Published
1973-04-00
Pages
526-9
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC444447
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.3.4.526 PMC Full Text View journal details
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