Differences in inducibility of cutaneous and hepatic drug metabolizing enzymes and cytochrome P-450 by polychlorinated biphenyls and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT).

Animals Benzopyrenes Carbon Monoxide Cyanides Cytochrome P-450 Enzyme System/metabolism DDT/pharmacology Enzyme Induction/drug effects Hemeproteins/metabolism Liver/enzymology Male Microsomes, Liver/enzymology Mixed Function Oxygenases/metabolism Oxidoreductases/metabolism Polychlorinated Biphenyls/pharmacology Rats Skin/enzymology Time Factors

Benzopyrenes Cyanides Hemeproteins Carbon Monoxide Cytochrome P-450 Enzyme System DDT Polychlorinated Biphenyls Mixed Function Oxygenases Oxidoreductases