Contraction of isolated smooth-muscle cells--structural changes.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 70 ·No. 3 ·1973-03-00 ·Pages 641-5

Fay FS, Delise CM

Abstract

The contraction of isolated smooth-muscle cells has been correlated with evagination of the cell membrane, a marked change in myofilament orientation, and a decrease in cellular volume. Both localized and full contractions have been elicited in the same cell by varying the intensity of electrical stimulation. These results may be explained by a model of the smooth-muscle cell in which the contractile apparatus extends between attachment sites on the cell membrane that are relatively closely spaced.

MeSH Terms

Animals Bufo marinus Cell Membrane Electric Stimulation Microscopy, Electron Microscopy, Electron, Scanning Muscle Contraction Muscle, Smooth/cytology Myofibrils Stomach/cytology

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Fay F S

Delise C M

References (9)

9 references, click to expand

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INFLUENCE OF OSMOTIC STRENGTH ON CROSS-SECTION AND VOLUME OF ISOLATED SINGLE MUSCLE FIBRES.
J Physiol. 1965 Mar;177:42-57 PMID: 14296959
Thick myofilaments in contracted and relaxed mammalian smooth muscle cells.
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Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.70.3.641

Published

1973-03-00

Pages

641-5

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC433324

Subset

External Links

PubMed source DOI: 10.1073/pnas.70.3.641 PMC Full Text View journal details

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