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PMID: 4192871 Published · ppublish English Journal Article

Vaccinia virus infection of synchronized pig kidney cells.

Journal of virology ·Vol. 1 ·No. 6 ·1967-12-00 ·Pages 1255-64

Groyon RM, Kniazeff AJ

Abstract

Vaccinia virus replication was studied in pig kidney (PK-15) cells synchronized by excess thymidine treatment. It was found that virus replication with concomitant inhibition of mitosis can occur at any period in the life cycle of the cell except for the narrow span of time from late prophase through telophase. Cells infected at this time continue to divide, and vaccinia does not replicate until cell division is complete.

MeSH Terms
Animals Cell Division/drug effects Cell Line Culture Techniques Kidney Microscopy, Electron Staining and Labeling Swine Thymidine/pharmacology Vaccinia virus/drug effects,growth & development Virus Replication/drug effects
Chemicals
Thymidine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Groyon R M
Kniazeff A J
References (24)
24 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.1.6.1255-1264.1967
Published
1967-12-00
Pages
1255-64
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC375416
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.1.6.1255-1264.1967 PMC Full Text View journal details
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