Gastric secretion during pregnancy and lactation in the rat.

The Journal of physiology ·Vol. 190 ·No. 2 ·1967-05-00 ·Pages 261-72

Lilja B, Svensson SE

Abstract

1. Gastric acid secretion has been studied in the rat before, during and after pregnancy using different types of stomach preparation. During the same periods the histamine-forming capacity (HFC) has been determined in gastric mucosa and mammary gland.2. In rats with a whole stomach fistula interdigestive acid secretion is increased during pregnancy and lactation.3. In rats with a denervated chronic pouch secretory response to stimulation with gastrin and histamine is augmented during pregnancy and lactation.4. The histamine forming capacity (HFC) of the gastric mucosa is increased 2-3 times during the last days of pregnancy and also during lactation.5. The HFC of the mammary gland is increased 2-3 times during lactation as compared with the fully developed gland in pregnancy.

MeSH Terms

Animals Female Fetus Gastric Juice/physiology Gastric Mucosa/physiology Gastrins/pharmacology Histamine Release Lactation Mammary Glands, Animal/physiology Pregnancy Pregnancy, Animal Rats Stomach/drug effects,physiology

Chemicals

Gastrins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Lilja B

Svensson S E

References (19)

19 references, click to expand

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Article Info

Journal

The Journal of physiology

Abbr.

J Physiol

ISSN

0022-3751

DOI

10.1113/jphysiol.1967.sp008206

Published

1967-05-00

Pages

261-72

Language

English

Region

England

NLM ID

0266262

PMCID

PMC1365291

Subset

External Links

PubMed source DOI: 10.1113/jphysiol.1967.sp008206 PMC Full Text View journal details

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Gastric secretion during pregnancy and lactation in the rat.

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