Long lasting stimulation of locomotor activity produced by the intraventricular injection of a cyclic analogue of dopamine into conscious mice.

Animals Blood Pressure/drug effects Cerebral Ventricles Cyclization Dopamine/administration & dosage,analogs & derivatives,pharmacology Fenclonine/pharmacology Haloperidol/pharmacology Heart Atria/drug effects Heart Rate/drug effects Injections Jejunum/drug effects Male Methyltyrosines/pharmacology Mice Motor Activity/drug effects Muscle Contraction/drug effects Muscle, Smooth/drug effects Norepinephrine/pharmacology Reserpine/pharmacology Serotonin Antagonists Stimulation, Chemical Time Factors Tyrosine 3-Monooxygenase/antagonists & inhibitors

Methyltyrosines Serotonin Antagonists Reserpine Tyrosine 3-Monooxygenase Haloperidol Fenclonine Dopamine Norepinephrine