Effects of prolonged treatment with adrenergic beta-receptor antagonists on blood pressure, cardiovascular design and reactivity in spontaneously hypertensive rats (SHR).

Administration, Oral Adrenergic beta-Antagonists/pharmacology Animals Blood Pressure/drug effects Depression, Chemical Dilatation Dose-Response Relationship, Drug Ethers/pharmacology Female Heart/drug effects Heart Rate/drug effects Heart Ventricles/drug effects Hypertension/drug therapy,prevention & control Isoproterenol/administration & dosage,pharmacology,therapeutic use Male Propanolamines/pharmacology Propranolol/administration & dosage,pharmacology,therapeutic use Propylamines/pharmacology Rats Time Factors Vascular Resistance/drug effects

Adrenergic beta-Antagonists Ethers Propanolamines Propylamines Propranolol Isoproterenol