Poly(2'-O-methylcytidylate)-oligodeoxyguanylate as a template for the ribonucleic acid directed deoxyribonucleic acid polymerase in ribonucleic acid tumor virus particles and a specific probe for the ribonucleic acid directed enzyme in transformed murine cells.

Animals Avian Leukosis Virus/enzymology Avian Sarcoma Viruses/enzymology Cell Transformation, Neoplastic Cells, Cultured/enzymology Cytosine Nucleotides/metabolism Deoxyribonucleases Deoxyribonucleotides/metabolism Guanine Nucleotides/metabolism Leukemia Virus, Feline/enzymology Leukemia Virus, Murine/enzymology Magnesium/pharmacology Manganese/pharmacology Methyl Ethers Mice Neurospora crassa/enzymology Nucleic Acid Hybridization Oligonucleotides/metabolism Oncogenic Viruses/enzymology Polynucleotides/metabolism RNA-Directed DNA Polymerase/metabolism Ribonucleases Species Specificity Structure-Activity Relationship Templates, Genetic Tritium

Cytosine Nucleotides Deoxyribonucleotides Guanine Nucleotides Methyl Ethers Oligonucleotides Polynucleotides Tritium Manganese RNA-Directed DNA Polymerase Deoxyribonucleases Ribonucleases Magnesium