The thymic suppressor cell. I. Separation of subpopulations with suppressor activity.

The Journal of experimental medicine ·Vol. 139 ·No. 1 ·1974-01-01 ·Pages 13-23

Ha TY, Waksman BH, Treffers HP

Abstract

This study confirms the finding that washed thymocytes from rats given 100 mg of BGG 48 h earlier, when transferred to syngeneic recipients, exert a specific suppressor effect on immunological responses to BGG in the latter. The active cells are found in a subpopulation of low density, making up less than 10% of the total thymocytes, and are partially resistant to hydrocortisone.

MeSH Terms

Animals Antibody Formation Hydrocortisone/pharmacology Immunity, Cellular Immunosuppression Therapy Luteinizing Hormone Lymphocytes/drug effects,immunology Male Rats T-Lymphocytes/immunology Thymus Gland/immunology gamma-Globulins

Chemicals

gamma-Globulins Luteinizing Hormone Hydrocortisone

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Ha T Y

Waksman B H

Treffers H P

References (25)

25 references, click to expand

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Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.139.1.13

Published

1974-01-01

Pages

13-23

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2139511

Subset

External Links

PubMed source DOI: 10.1084/jem.139.1.13 PMC Full Text View journal details

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The thymic suppressor cell. I. Separation of subpopulations with suppressor activity.

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