DNA content and DNA-based centromeric index of the 24 human chromosomes.

Science (New York, N.Y.) ·Vol. 179 ·No. 4078 ·1973-03-16 ·Pages 1126-9

Mendelsohn ML, Mayall BH, Bogart E, Moore DH, Perry BH

Abstract

The chromosomes of two human males were identified by fluorescent banding, restained, and measured by scanning microscopy and computer analysis. The two variables, DNA content and DNA-based centromeric index, provided almost complete discrimination of chromosome types. Some chromosomes showed significant differences in DNA content between the men, and for one man two pairs of chromosomes showed significant differences between homologs.

MeSH Terms

Adult Blood Cells/analysis,cytology Chromosomes/analysis Chromosomes, Human, 1-3/analysis Chromosomes, Human, 13-15/analysis Chromosomes, Human, 16-18/analysis Chromosomes, Human, 19-20/analysis Chromosomes, Human, 21-22 and Y/analysis Chromosomes, Human, 4-5/analysis Chromosomes, Human, 6-12 and X/analysis DNA/analysis Humans Karyotyping Male Sex Chromosomes/analysis Staining and Labeling

Chemicals

DNA

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Mendelsohn M L

Mayall B H

Bogart E

Moore D H

Perry B H

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.179.4078.1126

Published

1973-03-16

Pages

1126-9

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.179.4078.1126 View journal details

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