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PMID: 4117187 Published · ppublish English Journal Article

Occurrence of a theta-like antigen in rats.

The Journal of experimental medicine ·Vol. 136 ·No. 5 ·1972-11-01 ·Pages 1054-62

Douglas TC

Abstract

A rat antigen system parallel to the mouse theta system has been described(*) All rat strains tested expressed an antigen cross-reactive with the theta-AKR specificity of mice while none cross-reacted strongly with theta-C3H. The rat antigen may be demonstrated by either absorption or direct complement-mediated killing of rat thymocytes. Patterns of organ distribution and developmental appearance in the nervous system of rats also parallel those previously reported for theta in mice.

MeSH Terms
Animals Antigens Complement System Proteins Cross Reactions Cytotoxicity Tests, Immunologic Epitopes Immune Sera Immunization Mice Mice, Inbred AKR Mice, Inbred C3H Rabbits/immunology Rats Rats, Inbred Strains/immunology Species Specificity T-Lymphocytes/immunology
Chemicals
Antigens Epitopes Immune Sera Complement System Proteins
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Douglas T C
References (22)
22 references, click to expand
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Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
DOI
10.1084/jem.136.5.1054
Published
1972-11-01
Pages
1054-62
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2139293
Subset
IM
External Links
PubMed source DOI: 10.1084/jem.136.5.1054 PMC Full Text View journal details
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