Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. I. Stimulation of enzyme activity in nonhepatic cells and in hepatic cells by phenobarbital, polycyclic hydrocarbons, and 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane.

Animals Benz(a)Anthracenes/pharmacology Benzopyrenes Carbon Isotopes Cells, Cultured Chick Embryo Chromatography, Thin Layer Cricetinae DDT/pharmacology Enzyme Induction Extremities Fetus Gestational Age Half-Life Intestines Kinetics Liver/drug effects,enzymology Lung Methylcholanthrene/pharmacology Mice Mixed Function Oxygenases/biosynthesis,metabolism Phenobarbital/pharmacology Polycyclic Compounds Protein Biosynthesis RNA/biosynthesis Rabbits Rats Species Specificity Time Factors Tritium Uridine/metabolism

Benz(a)Anthracenes Benzopyrenes Carbon Isotopes Polycyclic Compounds Tritium Methylcholanthrene RNA DDT Mixed Function Oxygenases Uridine Phenobarbital