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PMID: 4058266 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The distribution and acyl composition of plasmalogens in guinea pig heart.

Lipids ·Vol. 20 ·No. 10 ·1985-10-00 ·Pages 693-8

Arthur G, Mock T, Zaborniak C, Choy PC

Abstract

In guinea pig heart homogenate, 34% of both choline and ethanolamine phosphoglycerides were in the form of plasmalogens (1-alkenyl, 2-acyl glycerophospholipid). Plasmalogens accounted for 39% of the choline phosphoglycerides and 36% of the ethanolamine phosphoglycerides in the mitochondrial fraction. Ethanolamine plasmalogen was the major ethanolamine phosphoglyceride (63%) in the guinea pig heart microsomal fraction. A high arachidonyl content was found in both diacyl and 1-alkenyl, 2-acyl glycerophosphoethanolamine. The C-2 fatty acyl profiles of the diacyl and 1-alkenyl, 2-acyl choline phosphoglycerides differed considerably from each other in the homogenate as well as in the subcellular fractions. Significant differences in the C-2 fatty acyl profiles also were observed in diacyl and 1-alkenyl, 2-acyl ethanolamine phosphoglycerides. Such differences suggest there is no direct metabolic relationship between the diacyl glycerophosphocholine (-ethanolamine) and its plasmalogen analog.

MeSH Terms
Acylation Animals Guinea Pigs Male Microsomes/analysis Mitochondria, Heart/analysis Myocardium/analysis Phosphatidylcholines/analysis Phosphatidylethanolamines/analysis Plasmalogens/isolation & purification Subcellular Fractions/analysis
Chemicals
Phosphatidylcholines Phosphatidylethanolamines Plasmalogens
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Arthur G
Mock T
Zaborniak C
Choy P C
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21 references, click to expand
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Article Info
Journal
Lipids
Abbr.
Lipids
ISSN
0024-4201
DOI
10.1007/BF02534389
Published
1985-10-00
Pages
693-8
Language
English
Region
United States
NLM ID
0060450
Subset
IM
External Links
PubMed source DOI: 10.1007/BF02534389 View journal details
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