Voltage- and current-clamp recordings of the receptor potential in olfactory receptor cells in situ.

Intracellular recordings obtained using the whole cell configuration of the patch recording technique show that isolated somas of olfactory receptor cells are electrogenic, producing fast overshooting action potentials when depolarized. In situ, these cells produce graded receptor potentials and action potentials when stimulated chemically. The receptor potential can be voltage clamped for analysis of the ionic basis of sensory transduction in olfaction.