Home LiteratureArticle Details
PMID: 4009189 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The effect of Parkinson's disease on the ability to maintain a mental set.

Journal of neurology, neurosurgery, and psychiatry ·Vol. 48 ·No. 6 ·1985-06-00 ·Pages 517-29

Flowers KA, Robertson C

Abstract

In two experiments with an Odd-Man-Out choice discrimination task, Parkinsonian subjects had difficulty in alternating between two rules on successive trials. The pattern of errors suggested that the difficulty arises from an instability of cognitive set rather than any loss of reasoning ability, perseveration or increased distractibility.

MeSH Terms
Adult Aged Choice Behavior Cognition Concept Formation Female Humans Male Middle Aged Neuropsychological Tests Parkinson Disease/psychology Set, Psychology
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Flowers K A
Robertson C
References (33)
33 references, click to expand
  1. Learning and memory in baboons with bilateral lesions of frontal or inferotemporal cortex.
    Nature. 1967 Jun 3;214(5092):1054-6 PMID: 4964235
  2. Critical analysis of the disability in Parkinson's disease.
    Mod Treat. 1968 Mar;5(2):257-82 PMID: 5655944
  3. W.A.I.S. scores in a group of Parkinson patients.
    Br J Psychiatry. 1969 May;115(522):555-6 PMID: 5806844
  4. Perseverative interference in monkeys following selective lesions of the inferior prefrontal convexity.
    Exp Brain Res. 1970 Nov 26;11(4):376-86 PMID: 4993199
  5. L-dopa: effect on highest integrative functions in Parkinsonism.
    Trans Am Neurol Assoc. 1970;95:250-2 PMID: 5514382
  6. Personality (MMPI) and cognitive (WAIS) changes after levodopa treatment.
    Arch Neurol. 1971 Aug;25(2):145-50 PMID: 4398328
  7. Intellectual functioning of persons with idiopathic Parkinsonism.
    J Nerv Ment Dis. 1972 Jun;154(6):445-52 PMID: 5030970
  8. Neural associations of the frontal cortex.
    Acta Neurobiol Exp (Wars). 1972;32(2):125-40 PMID: 4627612
  9. The frontal lobe system: cortical-subcortical interrelationships.
    Acta Neurobiol Exp (Wars). 1972;32(2):439-60 PMID: 4627619
  10. Parkinsonism: alterations in spatial orientation as determined by a route-walking test.
    Neuropsychologia. 1972 Sep;10(3):355-61 PMID: 5080496
  11. Psychiatric disturbances in Parkinson's disease.
    Dis Nerv Syst. 1972 Sep;33(9):577-83 PMID: 4649149
  12. Intellectual impairment in Parkinson's syndrome.
    Brain. 1972;95(2):405-12 PMID: 4655035
  13. The effect of type and area of brain lesion on Wisconsin card sorting test performance.
    Cortex. 1974 Jun;10(2):159-70 PMID: 4844468
  14. The extrapyramidal disorder of Alzheimer's disease.
    Eur Neurol. 1974;12(2):94-103 PMID: 4426320
  15. Parkinsonism: effects of levodopa treatment on concept formation.
    Neurology. 1975 Aug;25(8):701-4 PMID: 1171402
  16. A cyclic decision model of perceptual alternation.
    Perception. 1972;1(1):31-48 PMID: 4680924
  17. Cognitive deficits associated with chronic hepatic encephalopathy and their response to levodopa.
    J Neurol Neurosurg Psychiatry. 1975 Aug;38(8):794-8 PMID: 1185200
  18. A note of alterations of personal orientation in Parkinsonism.
    Neuropsychologia. 1976;14(4):425-9 PMID: 995236
  19. Effects of caudate nuclei or frontal cortex ablations in cats. IV. Bar pressing, maze learning, and performance.
    Exp Neurol. 1976 Dec;53(3):670-93 PMID: 1001393
  20. A modified card sorting test sensitive to frontal lobe defects.
    Cortex. 1976 Dec;12(4):313-24 PMID: 1009768
  21. Lack of prediction in the motor behaviour of Parkinsonism.
    Brain. 1978 Mar;101(1):35-52 PMID: 638725
  22. Neurochemistry of Parkinson's disease: relation between striatal and limbic dopamine.
    Adv Biochem Psychopharmacol. 1978;19:293-300 PMID: 696462
  23. The effect of symptom duration on cognitive and motor performance in parkinsonism.
    Neurology. 1979 Jul;29(7):951-6 PMID: 572944
  24. Parkinson's disease and Alzheimer's disease as disorders of the isodendritic core.
    Br Med J (Clin Res Ed). 1981 Dec 12;283(6306):1588-90 PMID: 6118194
  25. Perceptual motor dysfunction in Parkinson's disease: a deficit in sequential and predictive voluntary movement.
    J Neurol Neurosurg Psychiatry. 1983 Feb;46(2):145-51 PMID: 6842218
  26. Cognitive deficits in the early stages of Parkinson's disease.
    Brain. 1983 Jun;106 (Pt 2):257-70 PMID: 6850270
  27. Motor planning in Parkinson patients.
    Neuropsychologia. 1983;21(5):455-62 PMID: 6196678
  28. Dementia in Parkinson disease: a neuropsychological analysis.
    Brain Cogn. 1982 Jan;1(1):71-83 PMID: 6927555
  29. Effects of subcortical lesions in monkeys on visual-discrimination and single-alternation performance.
    J Comp Physiol Psychol. 1958 Aug;51(4):437-44 PMID: 13575600
  30. Perception of reversible figures after brain injury.
    AMA Arch Neurol Psychiatry. 1959 Jun;81(6):765-75 PMID: 13649013
  31. Comparison of the effects of frontal and caudate lesions on discrimination learning in monkeys.
    J Comp Physiol Psychol. 1962 Aug;55:458-63 PMID: 13865793
  32. Cognitive function in Parkinson's disease.
    J Nerv Ment Dis. 1962 Sep;135:196-205 PMID: 13984777
  33. JUDGMENT OF VISUAL AND POSTURAL VERTICAL BY PARKINSONIAN PATIENTS.
    Neurology. 1964 Apr;14:287-93 PMID: 14138674
Article Info
Journal
Journal of neurology, neurosurgery, and psychiatry
Abbr.
J Neurol Neurosurg Psychiatry
ISSN
0022-3050
Published
1985-06-00
Pages
517-29
Language
English
Region
England
NLM ID
2985191R
PMCID
PMC1028367
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com