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PMID: 3997491 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Increased chromosomal aberrations in first metaphases of cells isolated from the kidneys of aged mice.

Israel journal of medical sciences ·Vol. 21 ·No. 3 ·1985-03-00 ·Pages 296-301

Martin GM, Smith AC, Ketterer DJ, Ogburn CE, Disteche CM

Abstract

Chromosomal aberrations were scored in the first metaphases of cells isolated from the kidneys of young (8 months old) and aged (40 months old) CB6F1 mice. There was a sixfold increase in the frequency of such aberrations in metaphases from old mice as compared with young mice.

MeSH Terms

Aging Animals Cells, Cultured Chromosome Aberrations Karyotyping Kidney/cytology Male Metaphase Mice Mitotic Index

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Martin G M

Smith A C

Ketterer D J

Ogburn C E

Disteche C M

Article Info

Journal

Israel journal of medical sciences

Abbr.

Isr J Med Sci

ISSN

0021-2180

Published

1985-03-00

Pages

296-301

Language

English

Region

Israel

NLM ID

0013105

Subset

Grants

NIA NIH HHS · AG 00057 · United States

NIA NIH HHS · AG 01751 · United States

External Links

PubMed source

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Increased chromosomal aberrations in first metaphases of cells isolated from the kidneys of aged mice.

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