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PMID: 3959990 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Release of Fc-receptors after streptococcal lysis induced by a lytic enzyme from Streptomyces globisporus.

Medical microbiology and immunology ·Vol. 175 ·No. 1 ·1986-00-00 ·Pages 35-41

Tille D, Chhatwal GS, Blobel H

Abstract

Streptomyces globisporus produced an enzyme which had lytic effects on streptococci and was able to solubilize their Fc-receptors. A new method for rapid purification of this enzyme was described. It consisted of adsorption to Amberlite CG 50 and subsequent chromatography on CM-cellulose Whatman CM 52. The purified enzyme was free of proteases and had lysed streptococci of serological groups A, B, C, G and L. It released Fc-receptors from the streptococcal surface in a biologically active form.

MeSH Terms
Enzymes/isolation & purification Receptors, Fc/isolation & purification Solubility Streptococcus/metabolism Streptomyces/enzymology
Chemicals
Enzymes Receptors, Fc
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Tille D
Chhatwal G S
Blobel H
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30 references, click to expand
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Article Info
Journal
Medical microbiology and immunology
Abbr.
Med Microbiol Immunol
ISSN
0300-8584
DOI
10.1007/BF02123127
Published
1986-00-00
Pages
35-41
Language
English
Region
Germany
NLM ID
0314524
Subset
IM
External Links
PubMed source DOI: 10.1007/BF02123127 View journal details
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