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PMID: 3921529 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Influence of the staphylococcinlike peptide Pep 5 on membrane potential of bacterial cells and cytoplasmic membrane vesicles.

Journal of bacteriology ·Vol. 162 ·No. 2 ·1985-05-00 ·Pages 833-6

Sahl HG

Abstract

The staphylococcinlike peptide Pep 5 rapidly abolished the membrane potential of bacterial cells; active transport of amino acids by cytoplasmic membrane vesicles was inhibited and preaccumulated amino acids were released upon the addition of Pep 5. Artificial asolectin vesicles were not impaired by the peptide. It is concluded that the cytoplasmic membrane is the primary target of Pep 5.

MeSH Terms
Amino Acids/metabolism Bacillus subtilis/drug effects Bacteriocins/pharmacology Cell Membrane/drug effects Liposomes Membrane Potentials/drug effects Staphylococcus/drug effects
Chemicals
Amino Acids Bacteriocins Liposomes staphylococcin
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Sahl H G
References (12)
12 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.162.2.833-836.1985
Published
1985-05-00
Pages
833-6
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC218930
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.162.2.833-836.1985 PMC Full Text View journal details
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