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PMID: 3906567 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Nucleotide sequence encoding the biosynthetic dehydroquinase function of the penta-functional arom locus of Aspergillus nidulans.

Nucleic acids research ·Vol. 13 ·No. 22 ·1985-11-25 ·Pages 8119-28

Charles IG, Keyte JW, Brammar WJ, Hawkins AR

Abstract

The nucleotide sequence of a 1.9 Kb HindIII fragment of DNA derived from the arom locus of A.nidulans and encoding the biosynthetic dehydroquinase activity has been determined. The sequences encoding the biosynthetic and catabolic dehydroquinase enzymes of A.nidulans show no detectable homology, strongly suggesting convergent evolutionary pathways. The messenger RNA specified by the arom locus was detected as a 5.3 Kb RNA species.

MeSH Terms
Aspergillus nidulans/enzymology,genetics Base Sequence Biological Evolution Codon DNA, Recombinant/analysis Fungal Proteins/genetics,metabolism Genes Genes, Fungal Hydro-Lyases/genetics,metabolism Isoenzymes/genetics,metabolism Sequence Homology, Nucleic Acid
Chemicals
Codon DNA, Recombinant Fungal Proteins Isoenzymes Hydro-Lyases 3-dehydroquinate dehydratase
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Charles I G
Keyte J W
Brammar W J
Hawkins A R
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26 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/13.22.8119
Published
1985-11-25
Pages
8119-28
Language
English
Region
England
NLM ID
0411011
PMCID
PMC322114
Subset
IM
Databases
GENBANK
X03180, X03684, X05204
External Links
PubMed source DOI: 10.1093/nar/13.22.8119 PMC Full Text View journal details
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