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题目:: B-cell subsets: functional and structural characteristics.
作者:: Baum(C M),Davie(J M),McKearn(J P)
状态:: 发布时间1985-11-12 , 更新时间 2005-11-17
期刊:: Crit Rev Immunol
摘要:: The review will examine B-cell differentiation with an emphasis on B-cell subpopulations. We will begin with an analysis of current evidence concerning B-cell ontogeny. The development of the B-cell repertoire will be traced from stem cell to effector cells. The CBA/N mouse, which expresses an X-linked immunodeficiency, will serve as a basis for discussing the delineation of B cells into subpopulations. The CBA/N mouse provides evidence for distinct populations of B cells which can be differentiated by cell surface antigens as well as function. We intend to focus on the functional diversity of B-cell subpopulations and how they develop. The CBA/N mouse is not the only evidence for distinct B cell subpopulations and we will attempt to organize these data into a coherent story of B-cell subsets.
语言:: eng
DOI:

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