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PMID: 3891628 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Evolution of cell types and T-cell subsets in the spleens of Mycobacterium bovis BCG-resistant and M. bovis BCG-susceptible strains of mice after infection with M. bovis BCG.

Infection and immunity ·Vol. 49 ·No. 1 ·1985-07-00 ·Pages 253-5

Denis M, Forget A, Miailhe AC, Pelletier M, Skamene E

Abstract

In mice, the early host response to intravenous infection with small doses of dispersed Mycobacterium bovis BCG is controlled by the Bcg gene. After infection with a low dose of M. bovis BCG, Lyt-1+ cells were generated in the spleens of BCG-susceptible mice (Bcgs) in parallel with an increase in the proportion of phagocytic cells. Very few changes occurred in the splenic cell types of BCG-resistant mice (Bcgr).

MeSH Terms
Animals Antigens, Ly/analysis B-Lymphocytes/immunology Immunity, Innate Mice Mice, Inbred Strains/immunology Mycobacterium Infections/immunology Mycobacterium bovis/immunology Phagocytes/immunology Spleen/cytology,immunology T-Lymphocytes/immunology
Chemicals
Antigens, Ly
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Denis M
Forget A
Miailhe A C
Pelletier M
Skamene E
References (15)
15 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.49.1.253-255.1985
Published
1985-07-00
Pages
253-5
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC262087
Subset
IM
Grants
PHS HHS · A1 18693 · United States
External Links
PubMed source DOI: 10.1128/iai.49.1.253-255.1985 PMC Full Text View journal details
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