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PMID: 386354 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Identification and characterization of a self-regulated repressor of translocation of the Tn3 element.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 76 ·No. 8 ·1979-08-00 ·Pages 4020-4

Chou J, Casadaban MJ, Lemaux PG, Cohen SN

Abstract

Gene fusions that bring expression of the lacZ gene under control of transcriptional and trnaslational signals within the transposable element Tn3 have been used to study regulation of Tn3-specified proteins. A gene encoding a 21,355-Mr peptide that represses translocation of Tn3 and acts at the level oquenced; amber, missense, and cis-dominant (operator-constitutive) point mutations in this gene have been isolated and characterized.

MeSH Terms
Bacterial Proteins/biosynthesis,genetics Base Sequence DNA Transposable Elements Escherichia coli/genetics Genes, Regulator Lac Operon Molecular Weight Mutation Plasmids Repressor Proteins/physiology Transcription Factors/physiology
Chemicals
Bacterial Proteins DNA Transposable Elements Repressor Proteins Transcription Factors
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Chou J
Casadaban M J
Lemaux P G
Cohen S N
References (29)
29 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.76.8.4020
Published
1979-08-00
Pages
4020-4
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC383968
Subset
IM
Databases
GENBANK
M10719
External Links
PubMed source DOI: 10.1073/pnas.76.8.4020 PMC Full Text View journal details
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