Product induction of purine hydroxylase II in Asperigillus nidulans.

Molecular & general genetics : MGG ·Vol. 174 ·No. 1 ·1979-07-02 ·Pages 105-6

Sealy-Lewis HM, Lycan D, Scazzocchio C

Abstract

By the use of a mutation, hxB-20, that eliminates purine hydroxylase II activity but retains cross-reacting material and an ancillary NADH dehydrogenase activity, it has been established that 6-hydroxynicotinic acid rather than nicotinic acid, is the true inducer of purine hydroxylase II.

MeSH Terms

Aspergillus nidulans/genetics Enzyme Induction Mixed Function Oxygenases/biosynthesis Mutation Nicotinic Acids/pharmacology Purines/metabolism

Chemicals

Nicotinic Acids Purines Mixed Function Oxygenases

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Sealy-Lewis H M

Lycan D

Scazzocchio C

References (9)

9 references, click to expand

The genetic control of molybdoflavoproteins in Aspergillus nidulans. Allopurinol-resistant mutants constitutive for xanthine-dehydrogenase.
Eur J Biochem. 1973 Jul 16;36(2):428-45 PMID: 4581274
The genetic control of molybdoflavoproteins in Aspergillus nidulans. II. Use of NADH dehydrogenase activity associated with xanthine dehydrogenase to investigate substrate and product inductions.
Mol Gen Genet. 1973 Sep 5;125(2):147-55 PMID: 4149466
Molybdate metabolism in Aspergillus nidulans. I. Mutations affecting nitrate reductase and-or xanthine dehydrogenase.
Mol Gen Genet. 1970;108(2):129-45 PMID: 5475567
Oxidation of nicotinic acid by a Bacillus species: regulation of nicotinic acid and 6-hydroxynicotinic acid hydroxylases.
J Bacteriol. 1972 Oct;112(1):392-7 PMID: 5079068
A mutation defective in the xanthine alternative pathway of Aspergillus nidulans: its use to investigate the specificity of uaY mediated induction.
Mol Gen Genet. 1978 Sep 8;164(3):303-8 PMID: 362158
Studies on temperature-sensitive mutants affecting the assimilatory nitrate reductase of Aspergillus nidulans.
Eur J Biochem. 1974 Aug 15;47(1):107-10 PMID: 4611763
A COMMON CO-FACTOR FOR NITRATE REDUCTASE AND XANTHINE DEHYDROGENASE WHICH ALSO REGULATES THE SYNTHESIS OF NITRATE REDUCTASE.
Nature. 1964 Jan 4;201:58-60 PMID: 14085568
The induction and repression of the enzymes of purine breakdown in Aspergillus nidulans.
Biochim Biophys Acta. 1968 Sep 24;166(2):557-68 PMID: 5680610
REGULATORY MECHANISMS GOVERNING SYNTHESIS OF THE ENZYMES FOR TRYPTOPHAN OXIDATION BY PSEUDOMONAS FLUORESCENS.
J Gen Microbiol. 1964 May;35:319-34 PMID: 14179678

Article Info

Journal

Molecular & general genetics : MGG

Abbr.

Mol Gen Genet

ISSN

0026-8925

DOI

10.1007/BF00433311

Published

1979-07-02

Pages

105-6

Language

English

Region

Germany

NLM ID

0125036

Subset

External Links

PubMed source DOI: 10.1007/BF00433311

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Product induction of purine hydroxylase II in Asperigillus nidulans.

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