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PMID: 3818921 Published · ppublish English Case Reports Journal Article

Propionibacterium acnes osteomyelitis: case report and review of the literature.

Journal of clinical microbiology ·Vol. 25 ·No. 2 ·1987-02-00 ·Pages 251-4

Noble RC, Overman SB

Abstract

Propionibacterium acnes, a part of the skin flora, caused vertebral osteomyelitis in a man who had recently undergone a microdiskectomy. The identifying characteristics and antibiotic susceptibility pattern are presented for this unusual human pathogen. The relationship of P. acnes to bone infection is summarized for the first time. A typical patient with P. acnes osteomyelitis is an adult male who has had prior surgery. Most patients respond favorably to prolonged antibiotic therapy.

MeSH Terms
Adolescent Adult Aged Bacterial Infections/drug therapy,microbiology Child Female Humans Intervertebral Disc Displacement/surgery Lumbar Vertebrae Male Middle Aged Osteomyelitis/drug therapy,microbiology Penicillin G/therapeutic use Postoperative Complications Propionibacterium acnes/isolation & purification
Chemicals
Penicillin G
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Noble R C
Overman S B
References (39)
39 references, click to expand
  1. Anaerobic infections in children: a prospective study.
    Pediatrics. 1976 Mar;57(3):311-20 PMID: 1256941
  2. ANAEROBIC INFECTION OF THE BRAIN. OBSERVATIONS ON EIGHTEEN CONSECUTIVE CASES OF BRAIN ABSCESS.
    Am J Med. 1963 Nov;35:682-97 PMID: 14076021
  3. Anaerobic infections in children: a prospective survey.
    J Clin Microbiol. 1976 Mar;3(3):318-23 PMID: 1270594
  4. Acne arthralgia.
    J Bone Joint Surg Am. 1976 Jul;58(5):673-5 PMID: 132449
  5. Aerobically incubated thioglycolate broth disk method for antibiotic susceptibility testing of anaerobes.
    Antimicrob Agents Chemother. 1976 Oct;10(4):727-32 PMID: 984807
  6. Propionibacterium acnes: pathogen in central nervous system shunt infection. Report of three cases including immune complex glomerulonephritis.
    Am J Med. 1976 Dec;61(6):935-8 PMID: 137672
  7. Diphtheroid osteomyelitis.
    J Bone Joint Surg Am. 1977 Jun;59(4):527-30 PMID: 405396
  8. Anaerobic osteomyelitis.
    Medicine (Baltimore). 1978 Jan;57(1):83-103 PMID: 618443
  9. Bone infections involving anaerobic bacteria.
    Medicine (Baltimore). 1978 Jul;57(4):279-305 PMID: 207946
  10. Bone lesions in systemic acne (acne fulminans).
    Br J Dermatol. 1979 Jun;100(6):703-5 PMID: 157152
  11. Destructive arthritis associated with acne fulminans: a case report.
    Ann Rheum Dis. 1980 Aug;39(4):403-5 PMID: 6449180
  12. Acne rheumatism. Report of a case.
    J Rheumatol. 1981 Mar-Apr;8(2):336-9 PMID: 6453227
  13. Comparative in vitro activity of ceftizoxime, cefoperazone, and cefoxitin against anaerobic bacteria.
    Antimicrob Agents Chemother. 1981 Nov;20(5):683-5 PMID: 6275782
  14. Osteomyelitis of cervical spine from Propionibacterium acnes.
    Arthritis Rheum. 1982 Mar;25(3):346-8 PMID: 6461331
  15. Chronic sclerosing osteomyelitis (Garré).
    Clin Orthop Relat Res. 1982 Apr;(164):136-40 PMID: 7067276
  16. Intracranial epidural suppuration: the occult empyema.
    Neurosurgery. 1982 Sep;11(3):390-4 PMID: 7133355
  17. Recent experience with antimicrobial susceptibility of anaerobic bacteria: increasing resistance to penicillin.
    Mayo Clin Proc. 1982 Dec;57(12):737-41 PMID: 6923982
  18. Anaerobic osteomyelitis.
    J Bone Joint Surg Am. 1983 Jan;65(1):30-5 PMID: 6848532
  19. Unusual presentation of anaerobic osteomyelitis.
    Am J Med. 1983 Oct;75(4):724-6 PMID: 6624783
  20. [Corynebacterium acnes osteitis. A case in a child].
    Pediatrie. 1983 Jul-Aug;38(5):325-32 PMID: 6646947
  21. Role of anaerobic bacteria in bite-wound infections.
    Rev Infect Dis. 1984 Mar-Apr;6 Suppl 1:S177-83 PMID: 6372026
  22. Pyogenic osteomyelitis of the vertebral body.
    J Am Osteopath Assoc. 1984 Jun;83(10):724-8 PMID: 6746341
  23. Diphtheroid infections of man.
    Ann Intern Med. 1969 May;70(5):919-29 PMID: 4976893
  24. Latent corynebacterium acnes infection of bone marrow.
    N Engl J Med. 1969 Dec 18;281(25):1404-5 PMID: 5355456
  25. Serious infections caused by diphtheroids.
    Ann N Y Acad Sci. 1970 Oct 30;174(2):568-76 PMID: 5278136
  26. Corynebacterium: an oral-systemic pathogen: report of cases.
    J Oral Surg. 1971 May;29(5):349-51 PMID: 5280381
  27. Corynebacterium acnes in rheumatoid arthritis. I. Isolation and antibody studies.
    Ann Rheum Dis. 1972 Jan;31(1):22-7 PMID: 4621488
  28. Anaerobic bacteremia.
    Mayo Clin Proc. 1972 Sep;47(9):639-46 PMID: 5073944
  29. Anaerobic bacteria in late infections after total hip arthroplasty.
    Scand J Infect Dis. 1974;6(2):161-5 PMID: 4604093
  30. Role of anaerobic bacteria in subdural empyema. Report of four cases and review of 327 cases from the English literature.
    Am J Med. 1975 Jan;58(1):99-104 PMID: 234678
  31. Brain abscess: a review of recent experience.
    Ann Intern Med. 1975 Apr;82(4):571-6 PMID: 1168037
  32. Diphtheroid infection of the cervical spine.
    Acta Orthop Scand. 1975 Apr;46(1):67-70 PMID: 1136738
  33. Anaerobic pleuropulmonary infections. Clinical considerations.
    Cleve Clin Q. 1975 Spring;42(1):101-11 PMID: 806401
  34. Subdural empyema: analysis of 17 recent cases and review of the literature.
    Medicine (Baltimore). 1975 Nov;54(6):485-98 PMID: 1186492
  35. Diffuse sclerosing osteomyelitis of the mandible.
    Int J Oral Surg. 1984 Oct;13(5):363-85 PMID: 6437998
  36. Acne fulminans with osteolytic lesions.
    Arch Dermatol. 1985 May;121(5):662-4 PMID: 3158287
  37. Comparison of the PRAS II, AN-Ident, and RapID-ANA systems for identification of anaerobic bacteria.
    J Clin Microbiol. 1985 Jul;22(1):32-5 PMID: 3894412
  38. Comparative evaluation of three identification systems for anaerobes.
    J Clin Microbiol. 1985 Jul;22(1):52-5 PMID: 2862161
  39. Cerebrospinal fluid shunt infections with anaerobic diphtheroids (Propionibacterium species).
    J Neurosurg. 1976 May;44(5):580-4 PMID: 1262917
Article Info
Journal
Journal of clinical microbiology
Abbr.
J Clin Microbiol
ISSN
0095-1137
DOI
10.1128/jcm.25.2.251-254.1987
Published
1987-02-00
Pages
251-4
Language
English
Region
United States
NLM ID
7505564
PMCID
PMC265877
Subset
IM
External Links
PubMed source DOI: 10.1128/jcm.25.2.251-254.1987 PMC Full Text View journal details
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