Circulating immune complexes in serum from patients with dengue haemorrhagic fever.

Clinical and experimental immunology ·Vol. 36 ·No. 1 ·1979-04-00 ·Pages 46-53

Ruangjirachuporn W, Boonpucknavig S, Nimmanitya S

Abstract

Circulating immune complexes were detectable in 80% of serum from patients with dengue haemorrhagic fever. The immune complexes were detected for the first time on day two after the onset of the fever. The amount of complexes reached the maximum value on day 4 or 5 after onset, or when the patients developed shock or subsidence of fever, after which the complexes decreased in number. The number of complexes also correlated well with the clinical grading (severity) of the disease, i.e. the maximum amount was shown in grade III. These complexes may play a part in the pathogenesis of this disease.

MeSH Terms

Adolescent Antigen-Antibody Complex Child Child, Preschool Dengue/complications,immunology Fluorescent Antibody Technique Humans Latex Fixation Tests Shock/complications,immunology Time Factors

Chemicals

Antigen-Antibody Complex

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Ruangjirachuporn W

Boonpucknavig S

Nimmanitya S

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25 references, click to expand

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Article Info

Journal

Clinical and experimental immunology

Abbr.

Clin Exp Immunol

ISSN

0009-9104

Published

1979-04-00

Pages

46-53

Language

English

Region

England

NLM ID

0057202

PMCID

PMC1537690

Subset

External Links

PubMed source PMC Full Text View journal details

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Circulating immune complexes in serum from patients with dengue haemorrhagic fever.

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