Home LiteratureArticle Details
PMID: 3806793 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Identification of the gene encoding an RNA polymerase-binding protein of bacteriophage T4.

Journal of virology ·Vol. 61 ·No. 2 ·1987-02-00 ·Pages 597-9

Williams KP, Kassavetis GA, Esch FS, Geiduschek EP

Abstract

One of five bacteriophage T4-specified proteins that bind to host RNA polymerase core has been purified and partially sequenced. A mixed oligonucleotide, based on the amino acid sequence, was used to probe genomic restriction fragments. The gene for this protein, previously designated the 15K protein, has been located between T4 genes 45 and 46 and designated rpbA.

MeSH Terms
Amino Acid Sequence Base Sequence Carrier Proteins/genetics,isolation & purification DNA-Directed RNA Polymerases/metabolism Genes Genes, Viral T-Phages/enzymology,genetics Viral Proteins/genetics,isolation & purification
Chemicals
Carrier Proteins Viral Proteins DNA-Directed RNA Polymerases
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Williams K P
Kassavetis G A
Esch F S
Geiduschek E P
References (17)
17 references, click to expand
  1. Defining a bacteriophage T4 late promoter: bacteriophage T4 gene 55 protein suffices for directing late promoter recognition.
    Proc Natl Acad Sci U S A. 1984 Aug;81(16):5101-5 PMID: 6382259
  2. Polypeptide microsequence analysis with the commercially available gas-phase sequencer.
    Anal Biochem. 1984 Jan;136(1):39-47 PMID: 6424503
  3. Recognition sequences of restriction endonucleases and methylases--a review.
    Gene. 1985;33(1):1-102 PMID: 2985469
  4. Initiation of transcription by bacteriophage T4-modified RNA polymerase independently of host sigma factor.
    J Mol Biol. 1985 Sep 5;185(1):83-91 PMID: 4046041
  5. Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF.
    Proc Natl Acad Sci U S A. 1985 Oct;82(19):6507-11 PMID: 3863109
  6. Identification of two new bacteriophage T4 genes that may have roles in transcription and DNA replication.
    J Virol. 1987 Feb;61(2):366-74 PMID: 3543399
  7. New small polypeptides associated with DNA-dependent RNA polymerase of Escherichia coli after infection with bacteriophage T4.
    Proc Natl Acad Sci U S A. 1972 Mar;69(3):603-7 PMID: 4551978
  8. Polypeptide bound to the host RNA polymerase is specified by T4 control gene 33.
    Nat New Biol. 1973 Aug 1;244(135):137-40 PMID: 4579464
  9. Deoxyribonucleic acid dependent ribonucleic acid polymerases from two T4 phage-infected systems.
    Biochemistry. 1974 Jan 29;13(3):493-503 PMID: 4589313
  10. Two modes of in vivo transcription for genes 43 and 45 of phage T4.
    J Virol. 1974 Aug;14(2):341-8 PMID: 4847327
  11. Letter to the editor: Bacteriophage T4 transcriptional control gene 55 codes for a protein bound to Escherichia coli RNA polymerase.
    J Mol Biol. 1974 Nov 15;89(4):803-7 PMID: 4615168
  12. The interaction bacterial and phage proteins with immobilized Escherichia coli RNA polymerase.
    J Mol Biol. 1974 Sep 15;88(2):373-83 PMID: 4616088
  13. Detection of specific sequences among DNA fragments separated by gel electrophoresis.
    J Mol Biol. 1975 Nov 5;98(3):503-17 PMID: 1195397
  14. Genetic complementation by cloned bacteriophage T4 late genes.
    J Virol. 1981 Jul;39(1):31-45 PMID: 6456362
  15. Bacteriophage T4 gene 45. Sequences of the structural gene and its protein product.
    J Biol Chem. 1982 Aug 10;257(15):8972-9 PMID: 6284751
  16. Microisolation of neuropeptides.
    Methods Enzymol. 1983;103:72-89 PMID: 6142403
  17. The effect of a bacteriophage T4-induced polypeptide on host RNA polymerase interaction with promoters.
    J Biol Chem. 1984 Nov 10;259(21):13292-7 PMID: 6386813
Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.61.2.597-599.1987
Published
1987-02-00
Pages
597-9
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC253987
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.61.2.597-599.1987 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2