| GeneLibs

题目:: Binucleate cell formation correlates to loss of colony-forming ability in X-irradiated cultured mammalian cells.
作者:: Sasaki(H),Yoshinaga(H),Kura(S)
状态:: 发布时间1987-01-28 , 更新时间 2006-11-15
期刊:: Radiat Res
摘要:: The relationship between binucleate cell formation and the loss of colony-forming ability was examined in several cultured mammalian cell lines irradiated with X rays. The maximum fraction of binucleate cells after X irradiation increased dose-dependently within the range in which reproductive cell death might predominate over interphase cell death. When the logarithm of percentage survival was plotted against the percentage binucleate cells, a similar correlation was found for all cell lines tested, with the exception of mouse leukemia L5178Y cells, the most radiosensitive cells used. These observations suggest that the fraction of binucleate cells in the cell population can serve as a measure of cellular radiation damage.
语言:: eng
DOI:

文献库文献相关信息