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PMID: 3791721 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Evidence for anti-inflammatory effect of normal circulating plasma cortisol.

Clinical and experimental rheumatology ·Vol. 4 ·No. 4 ·1986-00-00 ·Pages 365-6

Saldanha C, Tougas G, Grace E

Abstract

Joint pain and tenderness increased significantly during metyrapone tests in 21 patients with rheumatoid arthritis who had never received corticosteroid therapy and who had no evidence of endocrine disease. This observation implies that the normal circulating plasma corticol exerts an anti-inflammatory effect.

MeSH Terms

Anti-Inflammatory Agents Arthritis, Rheumatoid/blood Humans Hydrocortisone/blood,physiology Hydroxycorticosteroids/urine Metyrapone/pharmacology

Chemicals

Anti-Inflammatory Agents Hydroxycorticosteroids Hydrocortisone Metyrapone

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Saldanha C

Tougas G

Grace E

Article Info

Journal

Clinical and experimental rheumatology

Abbr.

Clin Exp Rheumatol

ISSN

0392-856X

Published

1986-00-00

Pages

365-6

Language

English

Region

Italy

NLM ID

8308521

Subset

External Links

PubMed source View journal details

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Evidence for anti-inflammatory effect of normal circulating plasma cortisol.

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