Ciprofloxacin therapy for Mediterranean spotted fever.

Antimicrobial agents and chemotherapy ·Vol. 30 ·No. 4 ·1986-10-00 ·Pages 606-7

Raoult D, Gallais H, De Micco P, Casanova P

Abstract

We report the treatment of five patients with Mediterranean spotted fever with the antimicrobial agent ciprofloxacin. The treatment was administered intravenously for 2 days and then perorally for 8 days. All five patients were cured. These preliminary data seem to correlate with the in vitro activity of ciprofloxacin against Rickettsia conorii.

MeSH Terms

Adult Boutonneuse Fever/drug therapy Ciprofloxacin/blood,therapeutic use Female Humans Male

Chemicals

Ciprofloxacin

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Raoult D

Gallais H

De Micco P

Casanova P

References (5)

5 references, click to expand

[Malignant form of Mediterranean boutonneuse fever. 6 cases].
Presse Med. 1983 Oct 29;12(38):2375-8 PMID: 6226991
Pharmacokinetics of ciprofloxacin after oral and parenteral administration.
Antimicrob Agents Chemother. 1985 Mar;27(3):375-9 PMID: 3158275
Mediterranean spotted fever: clinical, laboratory and epidemiological features of 199 cases.
Am J Trop Med Hyg. 1986 Jul;35(4):845-50 PMID: 3728799
In vitro susceptibility of Rickettsia conorii to ciprofloxacin as determined by suppressing lethality in chicken embryos and by plaque assay.
Antimicrob Agents Chemother. 1986 Mar;29(3):424-5 PMID: 2940972
Mediterranean spotted fever: a cooperative study of 227 cases.
Rev Infect Dis. 1985 Sep-Oct;7(5):635-42 PMID: 3903943

Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.30.4.606

Published

1986-10-00

Pages

606-7

Language

English

Region

United States

NLM ID

0315061

PMCID

PMC176489

Subset

External Links

PubMed source DOI: 10.1128/AAC.30.4.606 PMC Full Text View journal details

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