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PMID: 3744563 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Passive immunization of hamsters against experimental infection with the Lyme disease spirochete.

Infection and immunity ·Vol. 53 ·No. 3 ·1986-09-00 ·Pages 713-4

Johnson RC, Kodner C, Russell M

Abstract

Hamsters passively immunized with as little as 0.0125 ml of immune rabbit serum (indirect fluorescent-antibody titer, 1:8,192) were protected from challenge with 1,000 50% infective doses of Borrelia burgdorferi. Cross-protection studies with Minnesota and Connecticut isolates of B. burgdorferi indicated no major differences in their capacity to elicit mutually protective antibodies in rabbits.

MeSH Terms
Animals Antibodies, Bacterial/analysis Borrelia/immunology Borrelia burgdorferi Cricetinae Female Immunization, Passive Lyme Disease/immunology Male Rabbits
Chemicals
Antibodies, Bacterial
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Johnson R C
Kodner C
Russell M
References (14)
14 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.53.3.713-714.1986
Published
1986-09-00
Pages
713-4
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC260855
Subset
IM
Grants
NIADDK NIH HHS · AM34744 · United States
External Links
PubMed source DOI: 10.1128/iai.53.3.713-714.1986 PMC Full Text View journal details
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