Participation of tumor killing factor in the antitumor effect of Sarcophaga lectin.

FEBS letters ·Vol. 201 ·No. 1 ·1986-05-26 ·Pages 37-40

Itoh A, Ohsawa F, Ohkuma Y, Natori S

Abstract

Antibody against tumor-killing factor inhibited cytotoxic activities produced in vitro by mouse peritoneal macrophages and in vivo in the serum of tumor-bearing mice in response to Sarcophaga lectin. These results suggest that tumor-killing factor participates in the antitumor effect of Sarcophaga lectin.

MeSH Terms

Animals Carcinoma, Ehrlich Tumor/immunology Cell Line Cytotoxicity Tests, Immunologic Cytotoxicity, Immunologic Diptera Glycoproteins/immunology Immune Sera/pharmacology Insect Proteins Lectins/pharmacology,therapeutic use Lectins, C-Type Macrophages/immunology Mice Neoplasms, Experimental/drug therapy,immunology Sarcoma 180/immunology Tumor Necrosis Factor-alpha

Chemicals

20kDa lectin protein, Sarcophaga Glycoproteins Immune Sera Insect Proteins Lectins Lectins, C-Type Tumor Necrosis Factor-alpha

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Itoh A

Ohsawa F

Ohkuma Y

Natori S

Article Info

Journal

FEBS letters

Abbr.

FEBS Lett

ISSN

0014-5793

DOI

10.1016/0014-5793(86)80566-x

Published

1986-05-26

Pages

37-40

Language

English

Region

England

NLM ID

0155157

Subset

Corrections

ErratumIn

External Links

PubMed source DOI: 10.1016/0014-5793(86)80566-x View journal details

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Participation of tumor killing factor in the antitumor effect of Sarcophaga lectin.

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