Meiotic recombination and synaptonemal complexes in Saccharomyces cerevisiae.

Molecular & general genetics : MGG ·Vol. 166 ·No. 2 ·1978-10-30 ·Pages 151-9

Olson LW, Zimmermann FK

Abstract

The course of meiotic recombination, gene conversion and crossing-over, was investigated in Saccharomyces cerevisiae. Gene conversion was used as the selected event by removing cells from a medium inducing and promoting meiosis to a vegetative growth medium selective for convertants. Gene conversion started to increase at the same time as DNA synthesis, and nuclei entered a phase where the chromatin appeared as thread-like structures. Crossing over of linked and unlinked markers also started early but remained at a low level until synaptonemal complexes were formed. However, gene conversion and a limited amount of crossing-over could be completed without synaptonemal complexes. It was concluded that meiotic recombination in yeast can occur as early as during DNA synthesis and does not require the function of synaptonemal complexes. Moreover, the low incidence of crossing-over early in meiosis is attributed to a low frequency of strand isomerization.

MeSH Terms

Alleles Crossing Over, Genetic Meiosis Recombination, Genetic Saccharomyces cerevisiae/cytology,genetics,physiology Spores, Fungal

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Olson L W

Zimmermann F K

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Article Info

Journal

Molecular & general genetics : MGG

Abbr.

Mol Gen Genet

ISSN

0026-8925

DOI

10.1007/BF00285917

Published

1978-10-30

Pages

151-9

Language

English

Region

Germany

NLM ID

0125036

Subset

External Links

PubMed source DOI: 10.1007/BF00285917

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Meiotic recombination and synaptonemal complexes in Saccharomyces cerevisiae.

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