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PMID: 370099 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Control of the receptor for galactose taxis in Salmonella typhimurium.

Journal of bacteriology ·Vol. 137 ·No. 2 ·1979-02-00 ·Pages 758-63

Fahnestock M, Koshland DE

Abstract

The chemotactic response to galactose in wild-type Salmonella typhimurium is not inducible by galactose, but is inducible by fucose, a non-metabolizable analog. In a galactokinase mutant, however, the galactose receptor is inducible by galactose. These data indicate that the concentration of free galactose in the cell controls the levels of the galactose receptor. The intensities of the chemotactic responses were found to vary in proportion to the concentration of galactose receptors. In bacteria with higher levels of galactose receptors, the ribose response is inhibited by galactose. This supports the model in which the ribose and galactose receptors compete for a common component of the signaling system.

MeSH Terms
Chemotaxis Fucose/metabolism Galactokinase/genetics Galactose/metabolism Mutation Receptors, Drug/metabolism Ribose/metabolism Salmonella typhimurium/genetics,physiology
Chemicals
Receptors, Drug Fucose Ribose Galactokinase Galactose
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Fahnestock M
Koshland D E
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24 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.137.2.758-763.1979
Published
1979-02-00
Pages
758-63
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC218354
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.137.2.758-763.1979 PMC Full Text View journal details
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