Home LiteratureArticle Details
PMID: 3653988 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Effect of immunization on experimental Bacteroides gingivalis infection in a murine model.

Infection and immunity ·Vol. 55 ·No. 10 ·1987-10-00 ·Pages 2534-7

Chen PB, Neiders ME, Millar SJ, Reynolds HS, Zambon JJ

Abstract

BALB/c mice were immunized with an invasive (A7A1-28) or noninvasive (381) Bacteroides gingivalis strain, Bacteroides intermedius, or Ringer solution. All immunized mice were subsequently challenged with the invasive B. gingivalis strain and examined for septicemia or secondary spread of the infection or both. Mice immunized with the invasive B. gingivalis strain localized the infection to the challenge site. Mice immunized with the noninvasive B. gingivalis strain, B. intermedius, or Ringer solution developed spreading infections. These data suggest that immunization with an invasive B. gingivalis strain can alter the course of subsequent infections.

MeSH Terms
Animals Bacteroides/immunology,pathogenicity Bacteroides Infections/immunology Disease Models, Animal Female Humans Immunization Mice Sepsis/prevention & control Virulence
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Chen P B
Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo 14214.
Neiders M E
Millar S J
Reynolds H S
Zambon J J
References (19)
19 references, click to expand
  1. Virulence of black-pigmented Bacteroides strains from periodontal pockets and other sites in experimentally induced skin lesions in mice.
    J Periodontal Res. 1982 Jan;17(1):41-9 PMID: 6123563
  2. Cellular immunity to Bacteroides fragilis capsular polysaccharide.
    J Exp Med. 1982 Apr 1;155(4):1188-97 PMID: 6174672
  3. New concepts of destructive periodontal disease.
    J Clin Periodontol. 1984 Jan;11(1):21-32 PMID: 6582072
  4. Black-pigmented Bacteroides species, Capnocytophaga species, and Actinobacillus actinomycetemcomitans in human periodontal disease: virulence factors in colonization, survival, and tissue destruction.
    J Dent Res. 1984 Mar;63(3):412-21 PMID: 6583243
  5. Brain abscess and cerebritis.
    Rev Infect Dis. 1984 Mar-Apr;6 Suppl 1:S101-6 PMID: 6718931
  6. Anaerobic infections in childhood.
    Rev Infect Dis. 1984 Mar-Apr;6 Suppl 1:S187-92 PMID: 6372028
  7. Use of a model of intraabdominal sepsis for studies of the pathogenicity of Bacteroides fragilis.
    Rev Infect Dis. 1984 Mar-Apr;6 Suppl 1:S91-5 PMID: 6372042
  8. Immunity to infection with Salmonella typhimurium: mouse-strain differences in vaccine- and serum-mediated protection.
    J Infect Dis. 1984 Sep;150(3):425-35 PMID: 6207248
  9. A soluble suppressor T cell factor protects against experimental intraabdominal abscesses.
    J Clin Invest. 1985 Mar;75(3):1023-7 PMID: 2579976
  10. Bacteroides endodontalis and other black-pigmented Bacteroides species in odontogenic abscesses.
    Infect Immun. 1985 Sep;49(3):494-7 PMID: 4030089
  11. Cellular control of abscess formation: role of T cells in the regulation of abscesses formed in response to Bacteroides fragilis.
    J Immunol. 1986 Jul 1;137(1):341-6 PMID: 3486915
  12. Comparison of living and nonliving vaccines for Brucella abortus in BALB/c mice.
    Infect Immun. 1986 Aug;53(2):245-51 PMID: 3089933
  13. The occurrence of Actinobacillus actinomycetemcomitans, Bacteroides gingivalis and Bacteroides intermedius in destructive periodontal disease in adults.
    J Clin Periodontol. 1986 Jul;13(6):570-7 PMID: 3462204
  14. Virulence factors of Bordetella pertussis.
    Annu Rev Microbiol. 1986;40:661-86 PMID: 2877614
  15. Selected characteristics of pathogenic and nonpathogenic strains of Bacteroides gingivalis.
    J Clin Microbiol. 1987 Apr;25(4):738-40 PMID: 3571482
  16. An experimentally induced phlegmonous abscess by a strain of Bacteroides gingivalis in guinea pigs and mice.
    Antonie Van Leeuwenhoek. 1981 Mar;47(1):1-9 PMID: 7247390
  17. Black-pigmented Bacteroides spp. in the human oral cavity.
    Infect Immun. 1981 Apr;32(1):198-203 PMID: 6111541
  18. Association of oral Bacteroides with gingivitis and adult periodontitis.
    J Periodontal Res. 1981 May;16(3):259-65 PMID: 6118402
  19. Virulence factors of anaerobic bacteria.
    Johns Hopkins Med J. 1982 Jul;151(1):1-9 PMID: 7045489
Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.55.10.2534-2537.1987
Published
1987-10-00
Pages
2534-7
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC260742
Subset
IM
Grants
NIDCR NIH HHS · DE06880 · United States
NIDCR NIH HHS · DE07497 · United States
NIDCR NIH HHS · DE07663 · United States
External Links
PubMed source DOI: 10.1128/iai.55.10.2534-2537.1987 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2