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PMID: 3653317 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Reacquisition of classical conditioning after removal of cerebellar cortex.

Experimental brain research ·Vol. 67 ·No. 3 ·1987-00-00 ·Pages 569-93

Lavond DG, Steinmetz JE, Yokaitis MH, Thompson RF

Abstract

We trained rabbits with white noise and light conditioned stimuli and a face shock unconditioned stimulus for classical conditioning of the nictitating membrane response and then removed the ipsilateral cerebellar cortex by aspiration. Larsell's hemisphere lobule VI was completely removed in 5 rabbits; the pattern of degeneration in the inferior olive matches the projections to HVI reported in experiments with horseradish peroxidase. All rabbits showed an initial abolition of conditioned responses but then relearned within two days. This indicates that cerebellar cortical lobule HVI normally is involved but is not necessary for classical conditioning.

MeSH Terms
Animals Behavior, Animal/physiology Cerebellar Cortex/physiology Conditioning, Classical/physiology Male Medical Illustration Rabbits
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Lavond D G
Department of Psychology, Stanford University, CA 94305.
Steinmetz J E
Yokaitis M H
Thompson R F
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Article Info
Journal
Experimental brain research
Abbr.
Exp Brain Res
ISSN
0014-4819
DOI
10.1007/BF00247289
Published
1987-00-00
Pages
569-93
Language
English
Region
Germany
NLM ID
0043312
Subset
IM
Grants
NINDS NIH HHS · 1 R23 NS2185301 · United States
External Links
PubMed source DOI: 10.1007/BF00247289 View journal details
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